This Saint, who had Nicomedia as his homeland, was the son of Eustorgius and Eubula. His father was an idolater, but his mother was a Christian from her ancestors. It was through her that he was instructed in piety, and still later, he was catechized in the Faith of Christ by Saint Hermolaus (see July 26) and baptized by him. Being proficient in the physician's vocation, he practiced it in a philanthropic manner, healing every illness more by the grace of Christ than by medicines. Thus, although his parents had named him Pantoleon ("in all things a lion"), because of the compassion he showed for the souls and bodies of all, he was worthily renamed Panteleimon, meaning "all-merciful." On one occasion, when he restored the sight of a certain blind man by calling on the Divine Name, he enlightened also the eyes of this man's soul to the knowledge of the truth. This also became the cause for the martyrdom of him who had been blind, since when he was asked by whom and in what manner his eyes had been opened, in imitation of that blind man of the Gospel he confessed with boldness both who the physician was and the manner of his healing. For this he was put to death immediately. Panteleimon was arrested also, and having endured many wounds, he was finally beheaded in the year 305, during the reign of Maximian. Saint Panteleimon is one of the Holy Unmercenaries, and is held in special honor among them, even as Saint George is among the Martyrs.

Saint Irene, who was from Cappadocia, flourished in the ninth century. Because of her great beauty and virtue, she was brought to Constantinople as a prospective bride for the young Emperor Michael (842-867); however, as Saint Joannicius the Great foretold, it was God's will that she assume the monastic habit instead. She shone forth in great ascetical labours, and suffered many attacks from the demons; while yet a novice, she attained to the practice of Saint Arsenius the Great, of praying the whole night long with arms stretched out towards Heaven (see May 8). God showed forth great signs and wonders in her, and she became the Abbess of the Convent of Chrysovalantou. She was granted the gift of clairvoyance and knew the thoughts of all that came to her. She appeared in a vision to the king and rebuked him for unjustly imprisoning a nobleman who had been falsely accused. Through a sailor from Patmos to whom he had appeared, Saint John the Evangelist sent her fragrant and wondrous apples from Paradise. She reposed at the age of 103, still retaining the youthful beauty of her countenance. After her repose, marvelous healings beyond number have been wrought by her to the present day.

The names of the Holy Maccabees are Abim, Anthony, Guria, Eleazar, Eusebona, Achim, and Marcellus. They were Jews by race and exact keepers of the Laws of the Fathers. They lived during the reign of Antiochus, who was surnamed Epiphanes ("Illustrious"), the King of Syria and an implacable enemy of the Jews. Having subjugated their whole nation and done many evil things to them, not sparing to assail the most sacred matters of their Faith, he constrained them, among other things, to partake of swine's flesh, which was forbidden by the Law. Then these pious youths, on being apprehended together with their mother and their teacher, were constrained to set at nought the Law, and were subjected to unspeakable tortures: wrackings, the breaking of their bones, the flaying of their flesh, fire, dismemberment, and such things as only a tyrant's mind and a bestial soul is able to contrive. But when they had endured all things courageously and showed in deed that the mind is sovereign over the passions and is able to conquer them if it so desires, they gloriously ended their lives in torments, surrendering their life for the sake of the observance of the divine Law. The first to die was their teacher Eleazar, then all the brethren in the order of their age. As for their wondrous mother Solomone, "filled with a courageous spirit, and stirring up her womanish thoughts with a manly wrath" (II Macc. 7:21), she was present at her children's triumph over the tyrant, strengthening them in their struggle for the sake of their Faith, and enduring stout-heartedly their sufferings for the sake of their hope in the Lord. After her last and youngest son had been perfected in martyrdom, when she was about to be seized to be put to death, she cast herself into the fire that they might not touch her, and was thus deemed worthy of a blessed end together with her sons, in the year 168 before Christ.