Saint Melania was a lady of noble birth, most wealthy and renowned, a descendant of Roman consuls, and of Spanish origin. When her husband and two of her children died, she departed for Egypt to visit the monks living at Mount Nitria. She distrubuted her wealth to those that were in need there, as well as to the confessors of the Faith who were being persecuted by the Arians. In three days alone, she fed some 5,000. Then, when these Orthodox Christians were exiled to Palestine, she also went to Jerusalem. There, at her own expense, she built a convent for virgins, and reposed therein in holiness about the year 410. Her granddaughter Melania the Younger is celebrated on December 31.

Saint Cyril of Belozersk, a Muscovite born in 1337, was tonsured in the Simonov Monastery in Moscow where he was later made abbot. Renouncing this position, at a revelation from the Mother of God he set out for the wilderness of Belozersk (White Lake) to live the life of a hermit. Later, when others desiring to lead the monastic life had gathered under his direction, he founded the Monastery of Belozersk. Throughout his life he had a very great reverence for the wonderworker, and was adorned with all the vitues, above all humility. Once, through the working of the enemy, one of his monks conceived an unendurable hatred for him; after being tormented by it for a whole year, he finally decided to reveal it to Cyril. When the monk was overcome with grief and shame at his malice towards such a venerable man, Cyril comforted him, affectionately telling him, "All the others are in error concerning me; only you have perceived my unworthiness," and forgiving him, sent him away in peace. Saint Cyril reposed on this day in 1427 at the age of ninety.

Saint Bartholomew was one of the Twelve Apostles, and had Galilee as his homeland; this is all that is known of him for certain according to the history of the Gospels. Concerning his apostolic work, certain say that he preached in Arabia and Persia, and especially in India, bringing to them the Gospel written by Saint Matthew, which had been written originally in Hebrew, and which was found there one hundred years later by Pantaenus, formerly a stoic philosopher and later an illustrious teacher of the Christian school in Alexandria (see Eusebius, Eccl. Hist., 5: 10). Other accounts say that he went to Armenia. According to some, he ended his life by being crucified, or by being flayed alive, in Albanopolis (Urbanopolis) of Armenia. This also confirms an ancient tradition preserved by the Armenians. According to some, Bartholomew and Nathanael are the same person, because the Evangelists who mention Bartholomew do not mention Nathanael; and John, who alone mentions Nathanael as one of the Twelve, says nothing of Bartholomew. Indeed, Bartholomew is a patronymic, "son of Talmai," which means "bold, spirited" (see also Jesus of Navi 15:14; II Kings 3:3), and Nathanael could have had this as a surname. According to the Synaxarion of the Menaion on April 22, however, it is Simon the Zealot and Nathanael who are the same; the Evangelists who mention Simon the Zealot (or "the Canaanite") do not mention Nathanael.

Saint Barnabas, one of the Seventy, was from Cyprus, of the tribe of Levi, and a fellow disciple with Paul under Gamaliel. He was called Joses, but was renamed Barnabas, which means "son of consolation," perhaps to distinguish him from the Joses called Barsabas and surnamed Justus (Acts 1:23). Saint Barnabas had a field, which he sold and brought the money to the Apostles (Acts 4:36-37). Before the conversion of Saul to Paul, it was Barnabas who was the leader of the Seventy Apostles, the first in preaching and chief spokesman. After Saul's vision on the road to Damascus, it was Barnabas who joined him to the Apostles when the others, because of Saul's reputation as a persecutor of the Church, still feared him (Acts 9:26-27); again it was Saint Barnabas who conscripted Paul as a preacher, bringing him from Tarsus to Antioch after the stoning of Stephen, to assist in spreading the Gospel (Acts 11:25-26). Saint Barnabas preached the Gospel in many places, traveled together with Paul, and finally was stoned to death by the Jews in his native Cyprus. During the reign of Zeno, in the year 478, his sacred relics were found, having on his chest the Gospel according to Matthew written in Greek by Barnabas' own hand. This Gospel was brought to Zeno. Because of this the Church of Cyprus received the right of autonomy, and its archbishop was given the privilege, like the emperor, of signing his decrees and encyclicals in vermilion.

The Synaxis of the Icon of the Most Holy Theotokos is celebrated today for the following reason: In 980, during the reign of Emperor Basil II, when Nicholas Chrysoberges was Ecumenical Patriarch, the holy Archangel Gabriel appeared in the guise of a monk to the disciple of a certain elder living in a hermitage belonging to the Monastery of Pantocrator on the Holy Mountain. During Matins, after the monk had chanted the customary hymn, "More honorable than the Cherubim...," composed by Saint Cosmas the Hymnographer, the Angel chanted the same hymn, but with the following prelude: "It is truly meet to call thee blest, the Theotokos, the ever-blessed and all-immaculate and Mother of our God." Marveling at the hymn's beauty, the monk asked his visitor - who appeared also to be a monk - to record this new text in writing, which the Angel did by miraculously inscribing the words on a piece of slate, using only his finger, and straightway he vanished from sight. This slate was brought to the Church of the Protaton, and from thence to Constantinople, to the imperial court and the Ecumenical Patriarchate, as evidence of the miracle. Henceforth, this version of the hymn to the Most Holy Theotokos began to be chanted in the Divine Liturgy in all the churches. The place where the miracle took place is now called Adein, from the Greek word which means "to sing." The icon itself, before which this hymn was first chanted, is called "the icon of the Axion estin" ("It is truly meet") and it is kept in the sanctuary of the Church of the Protaton on the Holy Mountain.

Saint Onuphrius flourished in the fourth century, first in the cenobium near Hermopolis of Thebes in Egypt, and later as a solitary in the desert, where he was discovered by Saint Paphnutius. When Paphnutius first encountered him deep in the desert, he was affrighted at the Saint's appearance, seeing him covered with hair like a wild beast and naked except for a garment sewn of leaves covering his loins. After relating his life and the bitter conflicts he had endured as a hermit, Onuphrius told Paphnutius that he was about to die, and that Paphnutius had been sent to bury him, which soon came to pass. Although Paphnutius desired afterwards to remain in the Saint's cave, as soon as he had buried him, the cave fell in and the palm tree, which had furnished the Saint with dates withered up, indicating that it was the will of God that Paphnutius return to his monastery and make Saint Onuphrius known to all.

Saint Peter was born of noble parents in Constantinople in the ninth century. Sent forth with the Roman army against the Saracens, he was taken captive and shut up in the prison of Samarra in Syria; this is no doubt the same prison in which the Forty-Two Martyrs of Amorion were kept (see Mar. 6). Released from prison through the prayers of Saint Nicholas of Myra and Saint Symeon the God-receiver, he fled to Rome, where he became a monk, and later came to the peninsula of Athos, where he lived in a cave as a solitary, suffering many temptations from the evil one, but also enjoying the manifest help of the most holy Theotokos. After many years, he reposed in peace.