This Saint, who was from the East, lived during the reign of Saint Theodosius the Younger. In 442 he enlisted in the Fourth Military Company of the Scholarii, that is, the Imperial Guard. Afterwards, he became a monk on a certain mountain in Bithynia (which later took his name), not far from Chalcedon. On becoming the archimandrite of the monastics gathered there, and proving himself to be most enduring in asceticism and most Orthodox in his faith, he reposed during the reign of the Emperor Leo the Great of Thrace, who reigned from 457 to 474.

This Apostle, who was from Colossae, was a bond-servant of that Philemon to whom the Apostle Paul addressed his epistle. Onesimus escaped from Philemon and fled to Rome, where he became a disciple of Saint Paul. Saint Paul brought him to the Faith of Christ, and then sent him back to his master, who in turn gave him his freedom and sent him back to Rome again, where he ministered to Saint Paul. Later, he was seized because he was a Christian and was sent to Puteoli, where he was beaten to death with clubs. Saint Onesimus is also commemorated on November 22 with the holy Apostles Philemon, Apphia, and Archippus.

This Martyr contested during the reign of Maximian, in the year 290, in Caesarea of Palestine, and was put to death by command of Firmilian, the Governor of Palestine. His fellow contestants' names are Valens, Paul, Seleucus, Porphyrius, Julian, Theodulus, and five others from Egypt: Elias, Jeremias, Esaias, Samuel, and Daniel. Their martyrdom is recorded in Book VIII, ch. 11 of Eusebius's Ecclesiastical History, called The Martyrs of Palestine.

Saint Theodore who was from Amasia of Pontus, contested during the reign of Maximian (286-305). He was called Tyro, from the Latin Tiro, because he was a newly enlisted recruit. When it was reported that he was a Christian, he boldly confessed Christ; the ruler, hoping that he would repent, gave him time to consider the matter more completely and then give answer. Theodore gave answer by setting fire to the temple of Cybele, the "mother of the gods," and for this he suffered a martyr's death by fire. See also the First Saturday of the Fast.

According to some, this Saint was born in Rome, but according to others in Tyrrenia (Tuscany), and was consecrated to the archiepiscopal throne of Rome in 440. In 448, when Saint Flavian, Archbishop of Constantinople, summoned Eutyches, an archimandrite in Constantinople, to give account for his teaching that there was only one nature in Christ after the Incarnation, Eutyches appealed to Saint Leo in Rome. After Saint Leo had carefully examined Eutyches's teachings, he wrote an epistle to Saint Flavian, setting forth the Orthodox teaching of the person of Christ, and His two natures, and also counseling Flavian that, should Eutyches sincerely repent of his error, he should be received back with all good will. At the Council held in Ephesus in 449, which was presided over by Dioscorus, Patriarch of Alexandria (and which Saint Leo, in a letter to the holy Empress Pulcheria in 451, was the first to call "The Robber Council"), Dioscorus, having military might behind him, did not allow Saint Leo's epistle to Flavian to be read, although repeatedly asked to do so; even before the Robber Council was held, Dioscorus had uncanonically received the unrepentant Eutyches back into communion. Because Saint Leo had many cares in Rome owing to the wars of Attila the Hun and other barbarians, in 451 he sent four delegates to the Fourth Ecumenical Council, where 630 Fathers gathered in Chalcedon during the reign of Marcian, to condemn the teachings of Eutyches and those who supported him. Saint Leo's epistle to Flavian was read at the Fourth Council, and was confirmed by the Holy Fathers as the Orthodox teaching on the incarnate person of our Lord; it is also called the "Tome of Leo." The Saint wrote many works in Latin; he reposed in 461. See also Saint Anatolius, July 3.

Saint Philothei was born in Athens in 1522 to an illustrious family. Against her will, she was married to a man who proved to be most cruel. When he died three years later, the Saint took up the monastic life and established a convent, in which she became a true mother to her disciples. Many women enslaved and abused by the Moslem Turks also ran to her for refuge. Because of this, the Turkish rulers became enraged and came to her convent, dragged her by force out of the church, and beat her cruelly. After a few days, she reposed, giving thanks to God for all things. This came to pass in the year 1589. She was renowned for her almsgiving, and with Saints Hierotheus and Dionysius the Areopagite is considered a patron of the city of Athens.

This Saint, who was from Ravenna in Italy, lived during the reign of Leo the Wise and his son Constantine Porphyrogenitus (end of the ninth and beginning of the tenth centuries). He struggled especially against the paganism and sorcery still prevalent in those regions.